In this podcast, I spend some time reviewing the HY chromosomes (from 1-22) and the classically tested factoids relating to their genetic diseases. I discuss the clinical/NBME presentations of these diseases. I also give some advice to M3s at the tail end of the podcast and a list of the chromosomes (quick drive by) that are necessary to know by exam (Step 1, Step 2CK). There are no attached slides.